During my PhD research, I developed a human lncRNA database LNCipedia (Volders et al., 2013; Volders et al., 2015). In this public resource, lncRNA transcripts are catalogued and annotated with information such as RNA structure, protein-coding potential, conservation, and literature if available. With over 200 citations and more than 150 visitors per day, our database has proven to be valuable for the lncRNA research community. Moreover, it has been key in the establishment of the lncRNA research at Ghent University. Currently, several research groups from different faculties have joined forces to unravel the role of lncRNAs in different developmental and disease contexts, relying on LNCipedia as state-of-the-art reference and on the non-coding RNA expertise present in the Vandesompele Lab.

My work in collaboration with the CompOmics lab (UGent/VIB) is focussed on using tandem mass spectrometry and machine learning to identify with high confidence (small) proteins encoded by miss-annotated lncRNAs.

Interests

  • Bioinformatics
  • Computational proteomics
  • Non-coding RNA

Education

  • PhD in Biomedical Sciences, 2015

    Ghent University

  • Master of Bioscience Engineering, 2011

    Ghent University

  • Bachelor of Biology, 2009

    Hasselt University

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