Publications

(2024). Interactome of the HIV-1 proteome and human host RNA. EMBO Reports.

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(2024). Leveraging a self-cleaving peptide for tailored control in proximity labeling proteomics. Cell Reports Methods.

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(2024). Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies. Molecular Oncology.

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(2023). Exploring the cell-free total RNA transcriptome in diffuse large B-cell lymphoma and primary mediastinal B-cell lymphoma patients as biomarker source in blood plasma liquid biopsies. Frontiers in Oncology.

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(2023). Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision. Nature Methods.

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(2023). mTOR Inhibition Enhances Delivery and Activity of Antisense Oligonucleotides in Uveal Melanoma Cells. Nucleic Acid Therapeutics.

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(2023). Patient-specific alterations in blood plasma cfRNA profiles enable accurate classification of cancer patients and controls. medRxiv.

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(2023). Benchmarking blood collection tubes and processing intervals for extracellular vesicle performance metrics. Journal of Extracellular Vesicles.

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(2023). Artifacts and biases of the reverse transcription reaction in RNA sequencing. RNA.

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(2023). Blocking Abundant RNA Transcripts by High-Affinity Oligonucleotides during Transcriptome Library Preparation. Biological Procedures Online.

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(2023). Longitudinal evaluation of serum microRNAs as biomarkers for neuroblastoma burden and therapeutic p53 reactivation. NAR Cancer.

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(2023). RNA Extraction Method Impacts Quality Metrics and Sequencing Results in Formalin-Fixed, Paraffin-Embedded Tissue Samples. Laboratory Investigation.

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(2022). Digital PCR-based evaluation of nucleic acid extraction kit performance for the co-purification of cell-free DNA and RNA. Human Genomics.

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(2022). Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study. bioRxiv.

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(2022). Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA. NAR Cancer.

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(2022). mRNA capture sequencing and RT-qPCR for the detection of pathognomonic, novel, and secondary fusion transcripts in FFPE tissue: a sarcoma showcase. International Journal of Molecular Sciences.

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(2022). A 3′‐end capture sequencing method for high‐throughput targeted gene expression profiling. Biotechnology Journal.

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(2022). Evaluation of efficiency and sensitivity of 1D and 2D sample pooling strategies for SARS-CoV-2 RT-qPCR screening purposes. Scientific reports.

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(2022). Unlocking the secrets of long non-coding RNAs in asthma. Thorax.

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(2022). CIRCprimerXL: Convenient and High-Throughput PCR Primer Design for Circular RNA Quantification. Frontiers in Bioinformatics.

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(2022). CiLiQuant: Quantification of RNA Junction Reads Based on Their Circular or Linear Transcript Origin. frontiers in Bioinformatics.

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(2022). RNA biomarkers from proximal liquid biopsy for diagnosis of ovarian cancer. Neoplasia.

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(2021). The Dangers of Using Cq to Quantify Nucleic Acid in Biological Samples: A Lesson From COVID-19. Clinical Chemistry.

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(2021). Custom long non-coding RNA capture enhances detection sensitivity in different human sample types. RNA Biology.

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(2021). Validation of Circular RNAs Using RT‐qPCR After Effective Removal of Linear RNAs by Ribonuclease R. Current Protocols.

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(2021). Messenger RNA capture sequencing of extracellular RNA from human biofluids using a comprehensive set of spike-in controls. Star Protocols.

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(2021). The RNA Atlas expands the catalog of human non-coding RNAs. Nature Biotechnology.

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(2020). Charting Extracellular Transcriptomes in The Human Biofluid RNA Atlas. Cell Reports.

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(2020). Candidate RNA biomarkers in biofluids for early diagnosis of ovarian cancer: A systematic review. Gynecologic Oncology.

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(2020). Benchmarking of cell type deconvolution pipelines for transcriptomics data. Nature Communications.

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(2020). Cautionary Note on Contamination of Reagents Used for Molecular Detection of SARS-CoV-2. Clinical Chemistry.

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(2020). When DNA gets in the way: A cautionary note for DNA contamination in extracellular RNA-seq studies. PNAS.

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(2020). Minimally invasive classification of paediatric solid tumours using reduced representation bisulphite sequencing of cell-free DNA: a proof-of-principle study. Epigenetics.

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(2020). The Digital MIQE Guidelines Update: Minimum Information for Publication of Quantitative Digital PCR Experiments for 2020. Clinical Chemistry.

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(2020). ER stress in antigen‐presenting cells promotes NKT cell activation through endogenous neutral lipids. EMBO reports.

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(2020). Genome-wide study of the effect of blood collection tubes on the cell-free DNA methylome. bioRxiv.

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(2020). Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development. EMBO reports.

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(2020). SPsimSeq: semi-parametric simulation of bulk and single-cell RNA-sequencing data. Bioinformatics.

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(2020). The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children: a review. European Journal of Pediatrics.

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(2020). Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis. Journal of Controlled Release.

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(2020). Closing the circle: current state and perspectives of circular RNA databases. Briefings in Bioinformatics.

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(2019). Performance assessment of total RNA sequencing of human biofluids and extracellular vesicles. Scientific Reports.

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(2019). Charting extracellular transcriptomes in The Human Biofluid RNA Atlas. bioRxiv.

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(2019). The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35. Nature Communications.

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(2019). The RNA Atlas, a single nucleotide resolution map of the human transcriptome. bioRxiv.

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(2019). Probabilistic index models for testing differential expression in single cell RNA sequencing data. bioRxiv.

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(2019). The generation and use of recombinant extracellular vesicles as biological reference material. Nature Communications.

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(2019). A comprehensive dataset of TLX1 positive ALL-SIL lymphoblasts and primary T-cell acute lymphoblastic leukemias. bioRxiv.

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(2019). SMARTer single cell total RNA sequencing. Nucleic Acids Research.

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(2019). Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes. Scientific Reports.

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(2019). Purification of high-quality RNA from a small number of fluorescence activated cell sorted zebrafish cells for RNA sequencing purposes. BMC Genomics.

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(2019). Evaluating the applicability of mouse SINEs as an alternative normalization approach for RT-qPCR in brain tissue of the APP23 model for Alzheimer’s disease. Journal of Neuroscience Methods.

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(2019). Cost-effective and robust genotyping using double-mismatch allele-specific quantitative PCR. Scientific Reports.

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(2018). Discovery and validation of a serum microRNA signature to characterize oligo- and polymetastatic prostate cancer: not ready for prime time. World Journal of Urology.

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(2018). A mechanistic classification of clinical phenotypes in neuroblastoma. Science.

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(2018). Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction. Gut.

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(2018). Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients. JCI Insight.

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(2018). In silico discovery of a FOXM1 driven embryonal signaling pathway in therapy resistant neuroblastoma tumors. Scientific Reports.

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(2018). Long noncoding RNA expression profiling in cancer: Challenges and opportunities. Genes, Chromosomes and Cancer.

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(2018). LNCipedia 5: towards a reference set of human long non-coding RNAs. Nucleic Acids Research.

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(2018). Targeted Genomic Screen Reveals Focal Long Non-Coding RNA Copy Number Alterations in Cancer Cell Lines. Non-Coding RNA.

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(2018). Differential gene expression analysis tools exhibit substandard performance for long non-coding RNA-sequencing data. Genome Biology.

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(2018). On determining the power of digital PCR experiments. Analytical and Bioanalytical Chemistry.

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(2018). A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing. Haematologica.

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(2018). Detecting long non-coding RNA biomarkers in prostate cancer liquid biopsies: Hype or hope?. Non-coding RNA Research.

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(2018). The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation. Oncogene.

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(2018). Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice. Scientific Reports.

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(2018). Comparative analysis of naive, primed and ground state pluripotency in mouse embryonic stem cells originating from the same genetic background. Scientific Reports.

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(2018). A high-throughput 3’ UTR reporter screening identifies microRNA interactomes of cancer genes. PLOS ONE.

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(2018). Cross-Cohort Analysis Identifies a TEAD4–MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma. Cancer Discovery.

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(2018). Localization and Expression of Nuclear Factor of Activated T-Cells 5 in Myoblasts Exposed to Pro-inflammatory Cytokines or Hyperosmolar Stress and in Biopsies from Myositis Patients. Frontiers in Physiology.

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(2018). Computational deconvolution of transcriptomics data from mixed cell populations. Bioinformatics.

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(2017). Prognostic and Therapeutic Implications of Circulating Androgen Receptor Gene Copy Number in Prostate Cancer Patients Using Droplet Digital Polymerase Chain Reaction. Clinical Genitourinary Cancer.

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(2017). The mutational landscape of MYCN, Lin28b and ALKF1174L driven murine neuroblastoma mimics human disease. Oncotarget.

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(2017). The mutational landscape of <i>MYCN, Lin28b</i> and <i>ALK<sup>F1174L</sup></i> driven murine neuroblastoma mimics human disease. Oncotarget.

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(2017). Evaluation of relative quantification of alternatively spliced transcripts using droplet digital PCR. Biomolecular Detection and Quantification.

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(2017). MicroRNA Expression Analysis Using Small RNA Sequencing Discovery and RT-qPCR-Based Validation. Methods in Molecular Biology,Functional Genomics.

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(2017). High-throughput PCR assay design for targeted resequencing using primerXL. BMC Bioinformatics.

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(2017). Expression Profiling Identifies the Noncoding Processed Transcript of HNRNPU with Proliferative Properties in Pancreatic Ductal Adenocarcinoma. Non-Coding RNA.

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(2017). A unified censored normal regression model for qPCR differential gene expression analysis. PLOS ONE.

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(2017). Quality control of digital PCR assays and platforms. Analytical and Bioanalytical Chemistry.

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(2017). Dual targeting of MDM2 and BCL2 as a therapeutic strategy in neuroblastoma. Oncotarget.

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(2017). Thermodynamic framework to assess low abundance DNA mutation detection by hybridization. PLOS ONE.

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(2017). Noncoding after All: Biases in Proteomics Data Do Not Explain Observed Absence of lncRNA Translation Products. Journal of Proteome Research.

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(2017). decodeRNA— predicting non-coding RNA functions using guilt-by-association. Database.

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(2017). Secretome analysis of breast cancer-associated adipose tissue to identify paracrine regulators of breast cancer growth. Oncotarget.

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(2017). Zipper plot: visualizing transcriptional activity of genomic regions. BMC Bioinformatics.

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(2017). MicroRNA-184 is a downstream effector of albuminuria driving renal fibrosis in rats with diabetic nephropathy. Diabetologia.

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(2017). Long non-coding RNAs in cutaneous melanoma: clinical perspectives. Oncotarget.

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(2017). Model-Based Classification for Digital PCR: Your Umbrella for Rain. Analytical Chemistry.

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(2017). Reply: Direct Detection of Circulating MicroRNAs Unveiled the Absence of MicroRNA-218-5p in Smoker Subjects. American Journal of Respiratory and Critical Care Medicine.

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(2017). EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research. Nature Methods.

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(2017). Erratum: Corrigendum: Differential expression of lncRNAs during the HIV replication cycle: an underestimated layer in the HIV-host interplay. Scientific Reports.

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(2016). miSTAR: miRNA target prediction through modeling quantitative and qualitative miRNA binding site information in a stacked model structure. Nucleic Acids Research.

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(2016). Depletion of tRNA-halves enables effective small RNA sequencing of low-input murine serum samples. Scientific Reports.

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(2016). The transcriptome of lung tumor-infiltrating dendritic cells reveals a tumor-supporting phenotype and a microRNA signature with negative impact on clinical outcome. OncoImmunology.

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(2016). Differential expression of lncRNAs during the HIV replication cycle: an underestimated layer in the HIV-host interplay. Scientific Reports.

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(2016). Stage 4S neuroblastoma tumors show a characteristic DNA methylation portrait. Epigenetics.

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(2016). MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma. Oncotarget.

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(2016). MicroRNA Profiling Reveals a Role for MicroRNA-218-5p in the Pathogenesis of Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine.

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(2016). Long non-coding RNA expression profiling in the NCI60 cancer cell line panel using high-throughput RT-qPCR. Scientific Data.

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(2016). Flexible analysis of digital PCR experiments using generalized linear mixed models. Biomolecular Detection and Quantification.

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(2016). Asthma inflammatory phenotypes show differential microRNA expression in sputum. Journal of Allergy and Clinical Immunology.

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(2016). Long noncoding RNA signatures define oncogenic subtypes in T-cell acute lymphoblastic leukemia. Leukemia.

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(2016). Melanoma addiction to the long non-coding RNA SAMMSON. Nature.

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(2016). RT-qPCR gene expression analysis in zebrafish. Methods in Cell Biology,The Zebrafish - Genetics, Genomics, and Transcriptomics.

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(2016). Straightforward and sensitive RT-qPCR based gene expression analysis of FFPE samples. Scientific Reports.

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(2016). DNA methylation profiling of primary neuroblastoma tumors using methyl-CpG-binding domain sequencing. Scientific Data.

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(2015). Renal microRNA- and RNA-profiles in progressive chronic kidney disease. European Journal of Clinical Investigation.

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(2015). Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma. Oncotarget.

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(2015). Targeted resequencing and variant validation using pxlence PCR assays. Biomolecular Detection and Quantification.

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(2015). Inhibition of CDK4/6 as a novel therapeutic option for neuroblastoma. Cancer Cell International.

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(2015). RNA expression signatures and posttranscriptional regulation in diabetic nephropathy. Nephrology Dialysis Transplantation.

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(2015). MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma. Cancer Letters.

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(2015). Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells. STEM CELLS.

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(2015). Comparison of RNA-seq and microarray-based models for clinical endpoint prediction. Genome Biology.

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(2015). RDML-Ninja and RDMLdb for standardized exchange of qPCR data. BMC Bioinformatics.

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(2015). Non-coding RNAs in the pathogenesis of COPD. Thorax.

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(2015). Identification of miRNAs contributing to neuroblastoma chemoresistance. Computational and Structural Biotechnology Journal.

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(2015). RT-qPCR-Based Quantification of Small Non-Coding RNAs. Methods in Molecular Biology,Small Non-Coding RNAs.

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(2015). Genome wide expression profiling of p53 regulated miRNAs in neuroblastoma. Scientific Reports.

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(2015). Individual patient risk stratification of high-risk neuroblastomas using a two-gene score suited for clinical use. International Journal of Cancer.

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(2014). Flexible, Scalable, and Efficient Targeted Resequencing on a Benchtop Sequencer for Variant Detection in Clinical Practice. Human Mutation.

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(2014). CASP8 SNP D302H (rs1045485) Is Associated with Worse Survival in MYCN-Amplified Neuroblastoma Patients. PLoS ONE.

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(2014). Ectopic MicroRNA-150-5p Transcription Sensitizes Glucocorticoid Therapy Response in MM1S Multiple Myeloma Cells but Fails to Overcome Hormone Therapy Resistance in MM1R Cells. PLoS ONE.

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(2014). Non-coding RNAs and respiratory disease. Thorax.

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(2014). An update on LNCipedia: a database for annotated human lncRNA sequences. Nucleic Acids Research.

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(2014). MiR-34a deficiency accelerates medulloblastoma formationin vivo. International Journal of Cancer.

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(2014). The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia. Haematologica.

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(2014). Expressed Repeat Elements Improve RT-qPCR Normalization across a Wide Range of Zebrafish Gene Expression Studies. PLoS ONE.

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(2014). Cancer-Associated Adipose Tissue Promotes Breast Cancer Progression by Paracrine Oncostatin M and Jak/STAT3 Signaling. Cancer Research.

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(2014). The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling. Journal of Extracellular Vesicles.

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(2014). Revised Risk Estimation and Treatment Stratification of Low- and Intermediate-Risk Neuroblastoma Patients by Integrating Clinical and Molecular Prognostic Markers. Clinical Cancer Research.

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(2014). MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia. Leukemia.

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(2014). miRBase Tracker: keeping track of microRNA annotation changes. Database.

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(2014). Illumina sequencing of 15 deafness genes using fragmented amplicons. BMC Research Notes.

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(2014). miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin. International Journal of Cancer.

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(2014). Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study. Nature Methods.

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(2014). Early Targets of miR-34a in Neuroblastoma. Molecular & Cellular Proteomics.

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(2014). MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia. Haematologica.

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(2014). Lung tumours reprogram pulmonary dendritic cell immunogenicity at the microRNA level. International Journal of Cancer.

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(2014). Selection of Reliable Reference Genes for RT-qPCR Analysis. Methods in Molecular Biology,Quantitative Real-Time PCR.

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(2014). Target enrichment using parallel nanoliter quantitative PCR amplification. BMC Genomics.

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(2014). Some cautionary notes on the petite "Holy Grail" of molecular diagnostics. Haematologica.

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(2014). Lack of association betweenMDM2promoter SNP309 and clinical outcome in patients with neuroblastoma. Pediatric Blood & Cancer.

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(2013). Pharmacologic activation of wild-type p53 by nutlin therapy in childhood cancer. Cancer Letters.

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(2013). The need for transparency and good practices in the qPCR literature. Nature Methods.

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(2013). Reference loci for RT-qPCR analysis of differentiating human embryonic stem cells. BMC Molecular Biology.

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(2013). Single-Nucleotide Polymorphisms and Other Mismatches Reduce Performance of Quantitative PCR Assays. Clinical Chemistry.

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(2013). Effective Alu Repeat Based RT-Qpcr Normalization in Cancer Cell Perturbation Experiments. PLoS ONE.

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(2013). The Digital MIQE Guidelines: Minimum Information for Publication of Quantitative Digital PCR Experiments. Clinical Chemistry.

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(2013). CLL Cells Respond to B-Cell Receptor Stimulation with a MicroRNA/mRNA Signature Associated with MYC Activation and Cell Cycle Progression. PLoS ONE.

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(2013). Regulatory microRNA Network Identification in Bovine Blastocyst Development. Stem Cells and Development.

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(2013). MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A. International Journal of Cancer.

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(2013). Focal DNA Copy Number Changes in Neuroblastoma Target MYCN Regulated Genes. PLoS ONE.

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(2012). Exon-level expression analyses identify MYCN and NTRK1 as major determinants of alternative exon usage and robustly predict primary neuroblastoma outcome. British Journal of Cancer.

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(2012). LNCipedia: a database for annotated human lncRNA transcript sequences and structures. Nucleic Acids Research.

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(2012). LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression. Nature Genetics.

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(2012). Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers. Genome Biology.

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(2012). Evaluation of qPCR curve analysis methods for reliable biomarker discovery: Bias, resolution, precision, and implications. Methods.

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(2012). Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nature Genetics.

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(2012). Identification of miR-145 as a Key Regulator of the Pigmentary Process. Journal of Investigative Dermatology.

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(2012). Synthetic lethality between Rb, p53 and Dicer or miR-17–92 in retinal progenitors suppresses retinoblastoma formation. Nature Cell Biology.

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(2012). Modulation of neuroblastoma disease pathogenesis by an extensive network of epigenetically regulated microRNAs. Oncogene.

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(2012). Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease. Thorax.

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(2012). Targeted Expression of Mutated ALK Induces Neuroblastoma in Transgenic Mice. Science Translational Medicine.

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(2012). Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation. Leukemia.

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(2012). Molecular diagnostics for congenital hearing loss including 15 deafness genes using a next generation sequencing platform. BMC Medical Genomics.

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(2012). MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells. Oncogene.

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(2012). Cancer Gene Prioritization for Targeted Resequencing Using FitSNP Scores. PLoS ONE.

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(2012). N-Cadherin in Neuroblastoma Disease: Expression and Clinical Significance. PLoS ONE.

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(2012). DNA methylation silences miR-132 in prostate cancer. Oncogene.

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(2012). Massively parallel sequencing for early molecular diagnosis in Leber congenital amaurosis. Genetics in Medicine.

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(2012). Accurate RT-qPCR gene expression analysis on cell culture lysates. Scientific Reports.

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(2011). miRNA Expression Profiling: From Reference Genes to Global Mean Normalization. Methods in Molecular Biology,Next-Generation MicroRNA Expression Profiling Technology.

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(2011). Whole-Genome RT-qPCR MicroRNA Expression Profiling. Methods in Molecular Biology,Functional Genomics.

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(2011). miRNA Expression Profiling Enables Risk Stratification in Archived and Fresh Neuroblastoma Tumor Samples. Clinical Cancer Research.

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(2011). Neuroblastoma epigenetics: From candidate gene approaches to genome-wide screenings. Epigenetics.

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(2011). Practical Tools to Implement Massive Parallel Pyrosequencing of PCR Products in Next Generation Molecular Diagnostics. PLoS ONE.

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(2011). Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma. Oncogene.

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(2011). The microRNA body map: dissecting microRNA function through integrative genomics. Nucleic Acids Research.

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(2011). Neuroblastoma genetics and phenotype: A tale of heterogeneity. Seminars in Cancer Biology.

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(2011). Identification of a novel recurrent 1q42.2-1qter deletion in high risk MYCN single copy 11q deleted neuroblastomas. International Journal of Cancer.

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(2011). Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma. International Journal of Cancer.

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(2011). High ALK Receptor Tyrosine Kinase Expression Supersedes ALK Mutation as a Determining Factor of an Unfavorable Phenotype in Primary Neuroblastoma. Clinical Cancer Research.

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(2011). EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells. British Journal of Haematology.

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(2011). Functional Analysis of the p53 Pathway in Neuroblastoma Cells Using the Small-Molecule MDM2 Antagonist Nutlin-3. Molecular Cancer Therapeutics.

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(2011). Primer Sequence Disclosure: A Clarification of the MIQE Guidelines. Clinical Chemistry.

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(2011). Measurable impact of RNA quality on gene expression results from quantitative PCR. Nucleic Acids Research.

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(2011). MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival. Cell Death & Differentiation.

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(2011). Hsa-mir-145 is the top EWS-FLI1-repressed microRNA involved in a positive feedback loop in Ewing's sarcoma. Oncogene.

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(2011). Differential mucosal expression of Th17-related genes between the inflamed colon and ileum of patients with inflammatory bowel disease. BMC Immunology.

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(2010). The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in Neuroblastoma. Molecular Cell.

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(2010). Correlation between porcinePPARGC1A mRNA expression and its downstream target genes in backfat andlongissimus dorsi muscle. Journal of Applied Genetics.

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(2010). MicroRNA Expression in Induced Sputum of Smokers and Patients with Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine.

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(2010). Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification. Clinical Cancer Research.

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(2010). Prognostic Impact of Gene Expression–Based Classification for Neuroblastoma. Journal of Clinical Oncology.

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(2010). Analysing 454 amplicon resequencing experiments using the modular and database oriented Variant Identification Pipeline. BMC Bioinformatics.

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(2010). Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma. Nucleic Acids Research.

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(2010). Multiplex Amplicon Quantification (MAQ), a fast and efficient method for the simultaneous detection of copy number alterations in neuroblastoma.. BMC Genomics.

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(2010). Accurate prediction of neuroblastoma outcome based on miRNA expression profiles. International Journal of Cancer.

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(2010). MicroRNA expression profiling to identify and validate reference genes for relative quantification in colorectal cancer. BMC Cancer.

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(2010). Chromosomal and MicroRNA Expression Patterns Reveal Biologically Distinct Subgroups of 11q- Neuroblastoma. Clinical Cancer Research.

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(2010). An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours. Oncogene.

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(2010). Improved Molecular Diagnostics of Idiopathic Short Stature and Allied Disorders: Quantitative Polymerase Chain Reaction-Based Copy Number Profiling ofSHOXand Pseudoautosomal Region 1. The Journal of Clinical Endocrinology & Metabolism.

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(2010). Accurate Outcome Prediction in Neuroblastoma across Independent Data Sets Using a Multigene Signature. Clinical Cancer Research.

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(2010). miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nature Cell Biology.

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(2010). Accurate and objective copy number profiling using real-time quantitative PCR. Methods.

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(2009). Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo. Cell Death & Differentiation.

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(2009). Selection of reference genes for quantitative real-time PCR in equine in vivo and fresh and frozen-thawed in vitro blastocysts. BMC Research Notes.

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(2009). How to do successful gene expression analysis using real-time PCR. Methods.

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(2009). MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors. Oncogene.

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(2009). RNA pre-amplification enables large-scale RT-qPCR gene-expression studies on limiting sample amounts. BMC Research Notes.

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(2009). Widespread Dysregulation of MiRNAs by MYCN Amplification and Chromosomal Imbalances in Neuroblastoma: Association of miRNA Expression with Survival. PLoS ONE.

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(2009). Antitumor Activity of the Selective MDM2 Antagonist Nutlin-3 Against Chemoresistant Neuroblastoma With Wild-Type p53. JNCI: Journal of the National Cancer Institute.

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(2009). 59-gene prognostic signature sub-stratifies high-risk neuroblastoma patients. The Lancet Oncology.

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(2009). Escape from p53-mediated tumor surveillance in neuroblastoma: switching off the p14ARF-MDM2-p53 axis. Cell Death & Differentiation.

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(2009). Comparison of miRNA profiles of microdissected Hodgkin/Reed-Sternberg cells and Hodgkin cell linesversusCD77+B-cells reveals a distinct subset of differentially expressed miRNAs. British Journal of Haematology.

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(2009). Amphiregulin and Epiregulin mRNA Expression in Primary Tumors Predicts Outcome in Metastatic Colorectal Cancer Treated With Cetuximab. Journal of Clinical Oncology.

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(2009). External oligonucleotide standards enable cross laboratory comparison and exchange of real-time quantitative PCR data. Nucleic Acids Research.

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(2009). External oligonucleotide standards enable cross laboratory comparison and exchange of real-time quantitative PCR data. Nucleic Acids Research.

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(2009). The emerging molecular pathogenesis of neuroblastoma: implications for improved risk assessment and targeted therapy. Genome Medicine.

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(2009). Chromosome 3p Microsatellite Allelotyping in Neuroblastoma: A Report on the Technical Hurdles. Cancer Investigation.

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(2009). A novel and universal method for microRNA RT-qPCR data normalization. Genome Biology.

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(2009). Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study. The Lancet Oncology.

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(2009). Meta-mining of Neuroblastoma and Neuroblast Gene Expression Profiles Reveals Candidate Therapeutic Compounds. Clinical Cancer Research.

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(2009). Unreliable Real-Time PCR Analysis of Human Endogenous Retrovirus-W (HERV-W) RNA Expression and DNA Copy Number in Multiple Sclerosis. AIDS Research and Human Retroviruses.

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(2009). The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments. Clinical Chemistry.

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(2009). RDML: structured language and reporting guidelines for real-time quantitative PCR data. Nucleic Acids Research.

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(2008). Positive correlation between relative mRNA expression of PRNP and SPRN in cerebral and cerebellar cortex of sheep. Molecular and Cellular Probes.

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(2008). RTPrimerDB: the portal for real-time PCR primers and probes. Nucleic Acids Research.

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(2008). High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA. Nucleic Acids Research.

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(2008). Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas. Genome Biology.

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(2008). Aberrant methylation of candidate tumor suppressor genes in neuroblastoma. Cancer Letters.

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(2008). Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project. Nature Biotechnology.

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(2008). CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23. BMC Cancer.

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(2008). Low-cost dedicated mini-arrays for high-throughput analysis of DNA copy-number alterations in neuroblastoma. Cancer Letters.

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