Latest

• OncoRNALab Team Shares Spin-Off Vision at HealthTech Investor Summit
• PhD fellow Elena Ramos gets second place in Promega's Rising Researchers Award
• A co-culture model to study modulators of tumor immune evasion through scalable arrayed CRISPR-interference screens
• Interactome of the HIV-1 proteome and human host RNA
• Stabilizing RNA in dried blood microsamples
• Congratulations to Dr. Morlion
• Unveiling cancer signals in liquid biopsy cell-free RNA profiles
• A doctorate as a flight
• Congratulations to Dr. Verwilt
• Advancing extracellular RNA research through method scrutiny, optimization, and mRNA integrity profiling
• mTOR Inhibition Enhances Delivery and Activity of Antisense Oligonucleotides in Uveal Melanoma Cells
• Shana's paper lands cover of Nucleic Acid Therapeutics
• Patient-specific alterations in blood plasma cfRNA profiles enable accurate classification of cancer patients and controls
• Pinpointing molecular mechanisms of long non-coding RNAs : at the crossroads of biochemistry and genetics
• Benchmarking blood collection tubes and processing intervals for extracellular vesicle performance metrics
• Artifacts and biases of the reverse transcription reaction in RNA sequencing
• Congratulations to Dr. Gysens
• Unlocking lncRNA functions through high-throughput CRISPR-interference screens in an in vitro airway inflammation model
• Blocking Abundant RNA Transcripts by High-Affinity Oligonucleotides during Transcriptome Library Preparation
• OncoRNALab lab weekend
• Longitudinal evaluation of serum microRNAs as biomarkers for neuroblastoma burden and therapeutic p53 reactivation
• Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
• A 3′‐end capture sequencing method for high‐throughput targeted gene expression profiling
• Evaluation of efficiency and sensitivity of 1D and 2D sample pooling strategies for SARS-CoV-2 RT-qPCR screening purposes
• Unlocking the secrets of long non-coding RNAs in asthma
• CiLiQuant: Quantification of RNA Junction Reads Based on Their Circular or Linear Transcript Origin
• Congratulations to Dr. Dewaele!
• RNA biomarkers from proximal liquid biopsy for diagnosis of ovarian cancer
• Congratulations to Dr. Hulstaert!
• Exploring RNA signatures in human biofluids as novel liquid biopsy tool
• Custom long non-coding RNA capture enhances detection sensitivity in different human sample types
• Messenger RNA capture sequencing of extracellular RNA from human biofluids using a comprehensive set of spike-in controls
• The RNA Atlas expands the catalog of human non-coding RNAs
• Congratulations to Dr. Lorenzi!
• Charting regulatory RNAs in the human transcriptome using RNA-sequencing
• Charting Extracellular Transcriptomes in The Human Biofluid RNA Atlas
• Candidate RNA biomarkers in biofluids for early diagnosis of ovarian cancer: A systematic review
• Benchmarking of cell type deconvolution pipelines for transcriptomics data
• When DNA gets in the way: A cautionary note for DNA contamination in extracellular RNA-seq studies
• To pool or not to pool?
• Evaluation of efficiency and sensitivity of 1D and 2D sample pooling strategies for diagnostic screening purposes
• Congratulations to Dr. Avila Cobos!
• Addressing challenges in transcriptome annotation and cell-type heterogeneity through integration of omics datasets and computational deconvolution
• Genome-wide study of the effect of blood collection tubes on the cell-free DNA methylome
• Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development
• OncoRNALab against corona
• Congratulations to Dr. Everaert!
• Development of extracellular RNA sequencing technologies and applications for cancer diagnosis and monitoring
• circRNA
• Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis
• Performance assessment of total RNA sequencing of human biofluids and extracellular vesicles
• Charting extracellular transcriptomes in The Human Biofluid RNA Atlas
• The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35
• The RNA Atlas, a single nucleotide resolution map of the human transcriptome
• The generation and use of recombinant extracellular vesicles as biological reference material
• LncRNAs as novel players in neuroblastoma tumor biology
• SMARTer single cell total RNA sequencing
• Congratulations to Prof. Vandesompele, Prof. De Preter, and Prof. Mestdagh for the prestigious Antoine Faes prize
• Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes
• Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients
• In silico discovery of a FOXM1 driven embryonal signaling pathway in therapy resistant neuroblastoma tumors
• Long noncoding RNA expression profiling in cancer: Challenges and opportunities
• LNCipedia 5: towards a reference set of human long non-coding RNAs
• Targeted Genomic Screen Reveals Focal Long Non-Coding RNA Copy Number Alterations in Cancer Cell Lines
• Differential gene expression analysis tools exhibit substandard performance for long non-coding RNA-sequencing data
• The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation
• Comparative analysis of naive, primed and ground state pluripotency in mouse embryonic stem cells originating from the same genetic background
• A high-throughput 3’ UTR reporter screening identifies microRNA interactomes of cancer genes
• Cross-Cohort Analysis Identifies a TEAD4–MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma
• Computational deconvolution of transcriptomics data from mixed cell populations
• The mutational landscape of <i>MYCN, Lin28b</i> and <i>ALK^F1174L</i> driven murine neuroblastoma mimics human disease
• The mutational landscape of MYCN, Lin28b and ALKF1174L driven murine neuroblastoma mimics human disease
• MicroRNA Expression Analysis Using Small RNA Sequencing Discovery and RT-qPCR-Based Validation
• Expression Profiling Identifies the Noncoding Processed Transcript of HNRNPU with Proliferative Properties in Pancreatic Ductal Adenocarcinoma
• Noncoding after All: Biases in Proteomics Data Do Not Explain Observed Absence of lncRNA Translation Products
• decodeRNA— predicting non-coding RNA functions using guilt-by-association
• Zipper plot: visualizing transcriptional activity of genomic regions
• Long non-coding RNAs in cutaneous melanoma: clinical perspectives
• MicroRNA-184 is a downstream effector of albuminuria driving renal fibrosis in rats with diabetic nephropathy
• Reply: Direct Detection of Circulating MicroRNAs Unveiled the Absence of MicroRNA-218-5p in Smoker Subjects
• EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research
• Erratum: Corrigendum: Differential expression of lncRNAs during the HIV replication cycle: an underestimated layer in the HIV-host interplay
• Depletion of tRNA-halves enables effective small RNA sequencing of low-input murine serum samples
• The transcriptome of lung tumor-infiltrating dendritic cells reveals a tumor-supporting phenotype and a microRNA signature with negative impact on clinical outcome
• Differential expression of lncRNAs during the HIV replication cycle: an underestimated layer in the HIV-host interplay
• MicroRNA Profiling Reveals a Role for MicroRNA-218-5p in the Pathogenesis of Chronic Obstructive Pulmonary Disease
• Long non-coding RNA expression profiling in the NCI60 cancer cell line panel using high-throughput RT-qPCR
• Asthma inflammatory phenotypes show differential microRNA expression in sputum
• CiLiQuant
• EV-TRACK
• LNCipedia
• miRBase Tracker
• ZipperPlot
• Melanoma addiction to the long non-coding RNA SAMMSON
• Straightforward and sensitive RT-qPCR based gene expression analysis of FFPE samples
• Renal microRNA- and RNA-profiles in progressive chronic kidney disease
• miRNome-wide high-throughput microRNA target identification
• Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells
• Non-coding RNAs in the pathogenesis of COPD
• Identification of miRNAs contributing to neuroblastoma chemoresistance
• RT-qPCR-Based Quantification of Small Non-Coding RNAs
• Genome wide expression profiling of p53 regulated miRNAs in neuroblastoma
• Ectopic MicroRNA-150-5p Transcription Sensitizes Glucocorticoid Therapy Response in MM1S Multiple Myeloma Cells but Fails to Overcome Hormone Therapy Resistance in MM1R Cells
• An update on LNCipedia: a database for annotated human lncRNA sequences
• MiR-34a deficiency accelerates medulloblastoma formationin vivo
• The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling
• miRBase Tracker: keeping track of microRNA annotation changes
• miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin
• Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study
• Early Targets of miR-34a in Neuroblastoma
• Lung tumours reprogram pulmonary dendritic cell immunogenicity at the microRNA level
• Effective Alu Repeat Based RT-Qpcr Normalization in Cancer Cell Perturbation Experiments
• CLL Cells Respond to B-Cell Receptor Stimulation with a MicroRNA/mRNA Signature Associated with MYC Activation and Cell Cycle Progression
• Regulatory microRNA Network Identification in Bovine Blastocyst Development
• MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A
• Focal DNA Copy Number Changes in Neuroblastoma Target MYCN Regulated Genes
• LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression
• LNCipedia: a database for annotated human lncRNA transcript sequences and structures
• Identification of miR-145 as a Key Regulator of the Pigmentary Process
• Synthetic lethality between Rb, p53 and Dicer or miR-17–92 in retinal progenitors suppresses retinoblastoma formation
• Accurate RT-qPCR gene expression analysis on cell culture lysates
• miRNA Expression Profiling: From Reference Genes to Global Mean Normalization
• Whole-Genome RT-qPCR MicroRNA Expression Profiling
• The microRNA body map: dissecting microRNA function through integrative genomics
• Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma
• Molecular portraits of non-coding RNAs in neuroblastoma
• EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells
• The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in Neuroblastoma
• MicroRNA Expression in Induced Sputum of Smokers and Patients with Chronic Obstructive Pulmonary Disease
• Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma
• Accurate prediction of neuroblastoma outcome based on miRNA expression profiles
• MicroRNA expression profiling to identify and validate reference genes for relative quantification in colorectal cancer
• miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
• Widespread Dysregulation of MiRNAs by MYCN Amplification and Chromosomal Imbalances in Neuroblastoma: Association of miRNA Expression with Survival
• Comparison of miRNA profiles of microdissected Hodgkin/Reed-Sternberg cells and Hodgkin cell linesversusCD77+B-cells reveals a distinct subset of differentially expressed miRNAs
• External oligonucleotide standards enable cross laboratory comparison and exchange of real-time quantitative PCR data
• External oligonucleotide standards enable cross laboratory comparison and exchange of real-time quantitative PCR data
• The emerging molecular pathogenesis of neuroblastoma: implications for improved risk assessment and targeted therapy
• A novel and universal method for microRNA RT-qPCR data normalization
• High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA